7 resultados para Overweight

em Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco


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[EN] Studies have reported a negative association between dairy product consumption and weight status. However, not as much research has focused on cheese; therefore, the aim of this study was to study the association between cheese intake and overweight and obesity in a representative Basque adult population. A food frequency questionnaire (FFQ) was obtained from a random sample of 1081 adults (530 males and 551 females, 17–96 years old). Cheese consumption data were expressed as g/1000 kcal/day. The prevalence of overweight/obesity was higher in men (55.1%) than in women (35.4%) (p50.001). Participants with low or moderate intake of fresh and processed cheese demonstrated a higher prevalence of excess weight, compared with those with higher consumption. The confounding variables selected in multivariate analysis were occupational status and age in both genders; and place of residence in men. In conclusion, negative associations were found between consumption of some types of cheese and overweight and obesity in this population.

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Haur-obesitatea gorputzeko gantz kantitatea gehiegizkoa izateari deritzo. Gaixotasun epidemiko kontsideratu den arren, urtero, prebalentzia goraka doa. Eritasun honek ondorio latzak ekar ditzake, besteak beste, beste hainbat gaixotasun eragin baititzake. Hori dela eta, prebentzioan lan egitea da biderik onena, eta horretarako, haur eta gurasoak arrisku faktoreei buruz informatzea da bide zuzena. Lan honen bitartez, gaixotasun honen prebentziorako suertatu diren interbentzio eraginkorrak aztertu eta horietan erizainaren funtzioa zehaztu nahi dugu. Horretarako, 2010 urteaz geroztik argitaratuta dauden ikerlanetan, eraginkortasuna baieztatuta duten prebentzio-programak bilatu dira Pubmed eta Scopus datu baseak erabilita. Bilaketan, entseiu klinikoak eta berrikuspen sistematikoak kontuan hartu dira eta horietan burutatuko interbentzio eraginkorrak aztertu dira. Behin hori edukita, horietan erizainak duen funtzioa aztertu eta prebentzioan duen garrantzia analizatu da. Horretaz aparte, frogatu gabe dauden interbentzio-programak ere aztertu dira, nahiz eta daturik eraginkortzat eman ez den, erizainak barnebiltzen dituen betebeharrak zehazteko eta prebentzioan duen erabilgarritasuna aztertzeko. Hainbat entseiu kliniko aztertu eta gero, haur-obesitatearen aurkako programak eraginkorrak direla ondorioztatu da. Gainera, erizainak hauetan paper garrantzitsua du, kontrolen segimendua eta obesitatearen inguruko heziketa azaltzen baitu. Honek konfidantza eta segurtasun nahikoa ematen die guraso zein umeei eta obesitatea pairatzeko probabilitatea gutxitzen du. Beraz, heziketa eraginkorra izan dadin eta prebentzioan lan egin ahal izateko, erizainak batez ere eskolako testuinguruan ume eta gurasoei eragiteko dituen gaitasunak jorratu dira. Erizainak, heziketa egokia jasoz gero, aholkuak emateko, ohitura-osasuntsuak sustatzeko, azterketa fisiko zein psikologikoa egiteko, zalantzak argitzeko eta konfidantza bermatzeko gai da.

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Este trabajo se encuentra bajo la licencia Creative Commons Attribution 3.0.

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Este trabajo se encuentra bajo la licencia Creative Commons Attribution 3.0.

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Background: Previous studies suggest that dietary protein might play a beneficial role in combating obesity and its related chronic diseases. Total, animal and plant protein intakes and their associations with anthropometry and serum biomarkers in European adolescents using one standardised methodology across European countries are not well documented. Objectives: To evaluate total, animal and plant protein intakes in European adolescents stratified by gender and age, and to investigate their associations with cardio-metabolic indicators (anthropometry and biomarkers). Methods: The current analysis included 1804 randomly selected adolescents participating in the HELENA study (conducted in 2006-2007) aged 12.5-17.5 y (47% males) who completed two non-consecutive computerised 24-h dietary recalls. Associations between animal and plant protein intakes, and anthropometry and serum biomarkers were examined with General linear Model multivariate analysis. Results: Average total protein intake exceeded the recommendations of World Health Organization and European Food Safety Authority. Mean total protein intake was 96 g/d (59% derived from animal protein). Total, animal and plant protein intakes (g/d) were significantly lower in females than in males and total and plant protein intakes were lower in younger participants (12.5-14.9 y). Protein intake was significantly lower in underweight subjects and higher in obese ones; the direction of the relationship was reversed after adjustments for body weight (g/(kg.d)). The inverse association of plant protein intakes was stronger with BMI z-score and body fat percentage (BF%) compared to animal protein intakes. Additionally, BMI and BF% were positively associated with energy percentage of animal protein. Conclusions: This sample of European adolescents appeared to have adequate total protein intake. Our findings suggest that plant protein intakes may play a role in preventing obesity among European adolescents. Further longitudinal studies are needed to investigate the potential beneficial effects observed in this study in the prevention of obesity and related chronic diseases.

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Cannabinoid CB1 receptors peripherally modulate energy metabolism. Here, we investigated the role of CB1 receptors in the expression of glucose/pyruvate/tricarboxylic acid (TCA) metabolism in rat abdominal muscle. Dihydrolipoamide dehydrogenase (DLD), a flavoprotein component (E3) of alpha-ketoacid dehydrogenase complexes with diaphorase activity in mitochondria, was specifically analyzed. After assessing the effectiveness of the CB1 receptor antagonist AM251 (3 mg kg(-1), 14 days) on food intake and body weight, we could identified seven key enzymes from either glycolytic pathway or TCA cycle-regulated by both diet and CB1 receptor activity-through comprehensive proteomic approaches involving two-dimensional electrophoresis and MALDI-TOF/LC-ESI trap mass spectrometry. These enzymes were glucose 6-phosphate isomerase (GPI), triosephosphate isomerase (TPI), enolase (Eno3), lactate dehydrogenase (LDHa), glyoxalase-1 (Glo1) and the mitochondrial DLD, whose expressions were modified by AM251 in hypercaloric diet-induced obesity. Specifically, AM251 blocked high-carbohydrate diet (HCD)-induced expression of GPI, TPI, Eno3 and LDHa, suggesting a down-regulation of glucose/pyruvate/lactate pathways under glucose availability. AM251 reversed the HCD-inhibited expression of Glo1 and DLD in the muscle, and the DLD and CB1 receptor expression in the mitochondrial fraction. Interestingly, we identified the presence of CB1 receptors at the membrane of striate muscle mitochondria. DLD over-expression was confirmed in muscle of CB1-/- mice. AM251 increased the pyruvate dehydrogenase and glutathione reductase activity in C2C12 myotubes, and the diaphorase/oxidative activity in the mitochondria fraction. These results indicated an up-regulation of methylglyoxal and TCA cycle activity. Findings suggest that CB1 receptors in muscle modulate glucose/pyruvate/lactate pathways and mitochondrial oxidative activity by targeting DLD.